Gabapentin for Fibromyalgia: How It Works, Dosage, and Side Effects
Understanding Gabapentin and Fibromyalgia Fibromyalgia is a chronic pain condition that affects the muscles and soft tissues, often leading to widespread pain, fatigue, and sleep disturbances. One of the medications frequently prescribed off-label for managing these symptoms is Gabapentin , also known by brand names such as Neurontin , Horizant , and Gralise . Although Gabapentin is not officially approved by the FDA for fibromyalgia, it has become popular due to its potential to balance neurotransmitters in the brain and reduce pain sensitivity, helping patients experience more manageable pain levels and improved rest. How Gabapentin Works Gabapentin works by influencing the activity of glutamate and gamma-aminobutyric acid (GABA) — two neurotransmitters that play a crucial role in regulating brain function and pain perception. In individuals with fibromyalgia, glutamate levels may be abnormally high, which overstimulates the nerve cells and increases pain sensi...